Laboratory of Biomaterials Innovations and Tissue Engineering (BITE)

Alireza Moshaverinia Lab
Photo of Dr. Alireza Moshaverinia

Principal Investigator:

Alireza Moshaverinia, D.D.S., M.S., Ph.D., F.A.C.P.

About

In BITE lab we focus of three trajectories:

  1. Development and characterization of novel biomaterials/dental biomaterials for tissue engineering and clinical applications
  2. Dental mesenchymal stem cell (MSC)-mediated craniofacial tissue engineering
  3. Analysis of the role of biomaterials in mesenchymal stem cell-immune cells cross-talk

Current Projects and Grants

  1. The role of elasticity of biomaterials on the stem cell-host immune cell interplay (NIDCR)
  2. Gingival mesenchymal stem cells as a novel treatment modality for periodontal tissue regeneration (CIRM)
  3. A novel stem cell based delivery system to improve bone tissue regeneration (NIDCR)
  4. Dopamer: Bioactive Dental Filling with Remineralization Power (UCLA Innovation Fund)

Publications

  • Hasani-Sadrabadi MM, Sarrion P, Pouraghaei S, Chau Y, Ansari S, Li S, Aghaloo T, Moshaverinia A*.An engineered cell-laden adhesive hydrogel promotes craniofacial bone tissue regeneration in rats. Sci Transl Med. 2020 Mar11;12(534).
  • Poubaghaie S, Mostarzadeh F, Chen C, Ansari S, Moshaverinia A*. Engineered microenvironment can induce differentiation of human gingival mesenchymal stem toward auditory progenitor cells. ACS Biomater Eng. 2020. doi.org/10.1021/acsbiomaterials.9b01795.
  • Hasani-Sadrabadi MM. Sarrion P, Nakatsuka N, Ansari, S, Aghaloo T, Khademhosseini A, Weiss PS, Moshaverinia A*. Hierarchically Patterned Polydopamine-Containing Membranes for Periodontal Tissue Engineering. ACS Nano, ACS Nano. 2019 Mar 21. doi: 10.1021
  • Hasani-Sadrabadi MM, Majedi FS, Bensinger SJ, Wu BM, Bouchard LS, Weiss PS, Moshaverinia A*. Mechanobiological Mimicry of Helper T Lymphocytes to Evaluate Cell-Biomaterial Cross-Talk. Adv Mater. 2018 Apr 23:e1706780. doi: 10.1002/adma.201706780.
  • Sevari SP, Shahnazi S, Chen C, Mitchell JC, Ansari S, Moshaverinia A*. Bioactive glass-containing hydrogel delivery system for osteogenic differentiation of human dental pulp stem cells. J Biomed Mater Res A. 2019 Nov 9. doi: 10.1002/jbm.a.36836

Lab Members

Collaborators

List of collaborators within and outside of UCLA:

UCLA:

  • Prof. Benjamin Wu
  • Prof. Paul Weiss
  • Prof. Song Li
  • Prof.Tara Aghaloo
  • Prof. Peter Moy
  • Prof. Cun-Yu Wang
  • Dr. Bo Yu
  • Prof. Mo Kang
  • Prof. Ichiro Nishimura

Outside UCLA:

  • Dr. Chider Chen (UPenn)
  • Prof. John Mitchell (Midwestern U)
  • Prof. Andre Pellegrin (Faculty of São Leopoldo Mandic, Campinas)
  • Prof. Boaz Arzi (UC Davis)

List of Lab Members:

  • Sahar Ansari, PhD (Lecturer/Project Scientist)
  • Sevda Pouagahei, MSc, Lab assistant

Opportunities

Please contact the PI.

Contact Us

(310) 794-6324
amoshaverinia@ucla.edu