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Jia Chang, D.D.S., Ph.D.
- 310-825-5543
UCLA School of Dentistry
10833 Le Conte Ave.
Box 951668
Los Angeles, CA 90095-1668
Dr. Jia Chang is an associate professor of the Section of Periodontics in the Division of Regenerative and Reconstructive Sciences.
Dr. Chang earned his dental degree in 1995 and completed his oral and maxillofacial surgery residency training in 1999 at Wuhan University in China. He then obtained a Ph.D. from Peking University in 2002. Dr. Chang completed further research training at the University of Michigan as a post-doctoral fellow and as an assistant researcher at UCLA. Dr. Chang completed his specialty training in Periodontology at the University of Michigan, Ann Arbor, in 2014. The following year, he became an American Board of Periodontology diplomate. Dr. Chang served as a full-time faculty member in periodontics at the University of Florida College of Dentistry for ten years before moving to UCLA.
At the UCLA School of Dentistry, Dr. Chang contributes to all aspects of teaching, research, patient care, and service assignments.
- Huang H, Lu J, Aukhil I, Yu C, Bhut B, Marchesan J, Pirih F, Chang J. FBXO11 regulates bone development. Bone. 2023 May;170:116709. doi: 10.1016/j.bone.2023.116709. Epub 2023 Mar 1. PMID: 36863499; PMCID: PMC11008459.
- Hakam AE, Vila G, Duarte PM, Mbadu MP, Ai Angary DS, Shuwaikan H, Aukhil I, Neiva R, da Silva HDP, Chang J. Effects of different antidepressant classes on dental implant failure: A retrospective clinical study. J Periodontol. 2021 Feb;92(2):196-204. doi: 10.1002/JPER.19-0714. Epub 2020 Aug 14. PMID: 32725908.
- Yu B, Chang J, Liu Y, Li J, Kevork K, Al-Hezaimi K, Graves DT, Park NH, Wang CY. Wnt4 signaling prevents skeletal aging and inflammation by inhibiting nuclear factor-κB. Nat Med. 2014 Sep;20(9):1009-17. PMID: 25108526; PMCID: PMC4159424.
- Chang J, Liu F, Lee M, Wu B, Ting K, Zara JN, Soo C, Al Hezaimi K, Zou W, Chen X, Mooney DJ, Wang CY. NF-κB inhibits osteogenic differentiation of mesenchymal stem cells by promoting β-catenin degradation. Proc Natl Acad Sci U S A. 2013 Jun 4;110(23):9469-74. PMID: 23690607; PMCID: PMC3677422.
- Chang J, Wang Z, Tang E, Fan Z, McCauley L, Franceschi R, Guan K, Krebsbach PH, Wang CY. Inhibition of osteoblastic bone formation by nuclear factor-kappaB. Nat Med. 2009 Jun;15(6):682-9. doi: 10.1038/nm.1954. PMID: 19448637; PMCID: PMC2768554.
- D.D.S., Wuhan University, China, 1995
- M.S., Oral and Maxillofacial Surgery, Wuhan University, China, 1999
- Ph.D., Oral and Maxillofacial Surgery, Peking University, China, 2002
- Postdoctoral Fellow, University of Michigan School of Dentistry, 2007
- Assistant Researcher, UCLA School of Dentistry, 2011
- M.S. and Certificate, Periodontics, University of Michigan, 2014
• Bone development and inflammation
• Oral tissue regeneration
• Molecular signaling in pathogenesis of periodontitis and periimplantitis
• Systemic effect of antidepressants on periodontal and implant health
- Diplomate, American Board of Periodontology
- American Academy of Periodontology
- American Dental Association
- International Association of Dental Research
- International Society of Bone Morphometry
- American Society for Bone and Mineral Research
- 2019, American Academy of Periodontology Volpe Basic Science Fellowship
- R01 Award 2019-2024, NIH/NIDCR
- R01 Award 2020-2025, NIH/NIDCR