Profile

Photo of Dr. Yong Kim

Yong  Kim,  Ph.D.

Professor-in-Residence
ykim@dentistry.ucla.edu
Phone
  • (310) 825-7210
Office
73-022 CHS
Address

UCLA School of Dentistry
10833 Le Conte Ave.
Box 951668
Los Angeles, CA 90095-1668

Classifications
  • Full-Time Faculty
Academic Sections
  • Biosystems and Function
Biography

Yong Kim, Ph.D.is a Professor-in-Residence in the Section of Biosystems and Function in the Division of Oral and Systemic Health Sciences at the UCLA School of Dentistry. He is also a member of UCLAs Jonsson Comprehensive Cancer Center and UCLA Broad Stem Cell Research Institute.

Representative Publications
  • Li, F., Wei, F., Huang, W.-L., Lin, C.-C., Li, L., Shen, M., Yan, Q., Liao, W., Chia, D., Tu, M., Tang, J., Feng, Z., Kim, Y., Su, W.-C., David Wong, D. Ultra-Short Circulating Tumor DNA (usctDNA) in Plasma and Saliva of Non-Small Cell Lung Cancer (NSCLC) Patients. (2020). Cancers 12(8), 2041.
  • Kaczor-Urbanowicz, K.E., Cheng, J., King, J.C., Sedarat, A., Pandol, S.J., Farrell, J., Wong, D.T.W., and Kim, Y. Reviews on current liquid biopsy for detection and management of pancreatic cancers. (2020). Pancreas (In Press)
  • Wang, Z., Li, F., Rufo, J., Chen, C., Yang, S., Li, L., Zhang, J, Kim, Y., Wu, M., Abemayor, E., Tu, M., Chia, D., Cheng, J., Spruce, R., Batis, N., Mehanna, H., T.W. Wong, D. T. W., and Huang. T. J. Acoustofluidic Salivary Exosome Isolation: A Liquid Biopsy Compatible Approach for Human Papillomavirus-Associated Oropharyngeal Cancer Detection. (2020). Journal of Molecular Diagnostics 22:50-59.
  • Kaczor-Urbanowicz, K. E., Wei, F., Rao, S. L., Kim, J., Shin, H., Cheng, J., Tu, M., D. T. W., and Kim, Y. Clinical validity of saliva and novel technology for cancer detection. (2019). BBA Reviews on Cancer 1872:49-59.
  • Das S. et al. The Extracellular RNA Communication Consortium: Establishing Foundational Knowledge and Technologies for Extracellular RNA Research. (2019). Cell 177:231-242.
  • Li, F., Yoshizawa, J.M., Kim, K.-M., Kanjanapangka, J., Grogan, T.R., Wang, X., Elashoff, D., Ishikawa, S., Chia, D., Akin, D., Yan, X., Lee, M.-S., Kang. S.-Y., Bae, J.-M., Sohn, T.-S., Lee, J.-H., Choi, M.-G., Min, B.-H., Lee, J.-H., Kim, J.-J., Kim, Y., Kim, S., Wong, D.T.W. (Co-corresponding author). Discovery and Validation of Salivary Extracellular RNA (exRNA) Biomarkers and Panel for Noninvasive Detection of Gastric Cancer. (2018). Clin. Chem. 64(10):1513-1521
  • Kim, Y.Y., Roubal, I., Lee, Y.S., Kim, J.S., Hoang, M., Mathiyakom, N., and Kim, Y. Alcohol-induced molecular dysregulation in human embryonic stem cell-derived neural precursor cells. (2016). PLoS ONE 11(9):e0163812.
  • Hoang, M., Kim, J.J., Kim, Y.Y., Tong, E., Trammell, B., Liu, Y., Shi, S., Yang, J., Hong, C., Wang, C.-Y., and Kim, Y. Alcohol-induced suppression of KDM6B dysregulates the mineralization potential in dental pulp stem cells. (2016). Stem Cell Research 17:111-121.
  • Liu, Y., Kou, X., Chen, C., Yu, J., Su, Y., Kim, Y., Shi, S., and Liu, Y. Chronic High Dose Alcohol Induces Osteopenia via Activation of mTOR Signaling in Bone Marrow Mesenchymal Stem Cells. (2016). Stem Cells 34(6):2157-68.
  • Cass, A., Bahn, J.H., Lee, J.-H., Greer, C., Lin, X., Kim, Y., Hsiao, Y.-H., Xiao, X. Global analyses of endonucleolytic cleavage in mammals reveal expanded repertoires of cleavage-inducing small RNAs and their targets (2016). Nucleic Acid Research 44(7):3253-3263.
Additional Information

Courses taught:

  • OB260 Oral Biology Seminar
  • OB201C Advanced Oral Pathobiology
  • OB275 Molecular and Cellular Biology
  • OSD211 Systems 5
  • OSD201 Block 2
Educational & Professional Background
  • B.S. Chemistry, Seoul National University, Seoul, Rep of Korea, 1985
  • M.S. Biochemistry & Molecular Biology, Mississippi State University, 1992
  • M.S. Biochemistry, University of Rochester, 1993
  • Ph.D. Biochemistry, University of Rochester,1998
Research & Interests
  • Study on the cellular and molecular function of cell cycle regulator in embryonic stem cell differentiation and embryo development.
  • Molecular determinants in the effects of teratogen in human stem cells.
  • Epigenetic regulation in embryonic stem cell differentiation and cancer development.
  • Role of CDK2AP1 in cell cycle regulation and the significance of its differential expression in cellular transformation in relation to checkpoint regulation and apoptosis.
  • Translational application of cell cycle regulatory mechanism for head and neck/oral cancer treatment.
  • Liquid biopsy for cancer detection using cancer-associated oncogenic mutations
Publications
Professional Memberships
  • American Association for Cancer Research: Associate member since 1998.
  • American Association for the Advancement of Science: member since 2000.
  • International Association for Dental Research: member since 2002.
  • International Society for Stem Cell Research: member since 2011.
  • Research Society on Alcoholism: member since 2018.
Awards
  • California Institute of Regenerative Medicine Basic Biology Award
  • R01 NIH/NIAAA
  • R21 NIH/NIAAA
  • UH2/UH3 NIH/NCATS
  • UG3/UH3 NIH/NCATS
  • TRDRP
  • JCCC SEED Fund