C. Julie Chang, Ph.D.
- (310) 267-3340
UCLA School of Dentistry
10833 Le Conte Ave.
Los Angeles, CA 90095-1668
C. Julie Chang has been promoted to Adjunct Assistant professor after joining School of Dentistry from the University of Texas McGovern Medical School. She is an experienced molecular microbiologist and has been studied bacterial pathogenesis with Dr. Ton-That since 2009 in the Department of Microbiology and Molecular Genetics. She has served as an important role in supervising graduate and postgraduate students and laboratory management. Additionally, she has led and collaborated in many research projects, whose results were published in highly respected peer-reviewed journals.
- Chang, C., Amer, B. R., Osipiuk, J., McConnell, S. A., Huang, I-H., Hsieh, V., Fu, J., Nguyen,H.H., Muroski,J., Flores, E., Ogor-zalek Loo, R.R., Loo, J. A., Putkey, J. A., Joachimiak, A., Das, A., Clubb, R.T. and Ton-That, H.ÊIn vitroÊreconstitution of sortase-catalyzed pilus polymerization reveals structural elements involved in pilin crosslinking. Proc Natl Acad Sci115(24): E5477-E5486. (2018)
- McConnell, S.A., Amer, B. R., Muroski,J., Fu, J., Chang, C., Ogor-zalek Loo, R.R., Loo, J. A., Osipiuk, J., Ton-That, H. and Clubb, R.T. Protein labeling via a specific lysine-isopeptide bond using the pilin polymerizing sortase from Corynebacterium diphtheria. J Am Chem Soc.140(27):8420-8423. (2018)
- Sanchez, B.C.*, Chang, C.*, Wu, C., Tran, B. and Ton-That, H. (2017) Electron transport chain is biochemically linked to pilus assembly required for polymicrobial interactions and biofilm formation in the Gram-positive Actinobacterium Actinomyces oris. MBio8(3). *These authors contributed equally to this work. (2017)
- Echelman, D., Alegre-Cebollada, J., Badilla, C.L., Chang, C., Ton-That, H. and Fern‡ndez, J.M. Cna-A domains in bacterial pili are efficient dissipaters of large mechanical shocks. Proc Natl Acad Sci 113(9):2490-5. (2016)
- Chang. C., Hung, I-H, Hendrickx, A. and Ton-That, H. Visualization of Gram-positive Bacterial Pili in the Bacterial Cell Surface, Methods in Molecular Biology, Ed. Anne Delcour 966: 77-95, Humana Press. (2013)
B.S. in Biology, Tunghai University, Taichung, Taiwan, 1984
Ph.D. in Microbiology, Texas A&M University, College Station, Texas, 1994
Oral Bacterial Pathogenesis
Protein Biochemistry and Engineering
Innovation for Therapeutical Treatment of Oral and Dental Diseases
- American Society for Microbiology
- U.S. Patent No. 5,777,078: Triggered Pore Forming Agents